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Innovate the way we see life | Tomocube Inc. | March 2024

Recent advances in label-free imaging and quantification techniques for studying lipid droplets

An article, hot off the press and recently published in Current Opinion in Cell Biology, presents a comprehensive overview of the current status of label-free imaging techniques in lipid droplet (LD) research.

The article emphasizes the significance of two imaging techniques, holotomography (HT) and vibrational spectroscopic imaging, in advancing our understanding of LD biology and their potential clinical implications.

Visit the article to see how these techniques may transform the rapidly evolving landscape of lipid droplet biology.

Label-free, long term monitoring of adipogenesis process

Recent research introduces a novel 3D live-cell imaging and analysis method which allows label-free investigation of adipocyte redifferentiation process in 42 days. Automated image analysis quantifies adipocytes and LD biophysical parameters, offering detailed subcellular adipogenesis profiles.

The key benefit of this low-coherence holotomography method lies in its ability to overcome challenges in traditional methodologies, such as labor-intensive sample preparation, cellular damage, and limited observation timeframes.

Lipid droplets in scientific literature: through Holotomography's insightful lens

Welcome to our #HolotomographyApplicationSeries.

Join us on a journey through groundbreaking scientific exploration as we introduce a series of 6 publications showcasing the unparalleled capabilities of Tomocube Holotomography system in lipid analysis-related research.

Gain unique insights into the boundless potential of label-free 3D live cell imaging technology in reshaping the landscape of scientific inquiry and medical innovation.