HT series

Revolutionary holotomography opens a new era in label-free live cell imaging

Cellular analysis plays a crucial role in a wide variety of research and diagnostic activities in life sciences. However, the information available to researchers and clinicians is limited by current microscopy techniques. An innovative new tool – Holotomographic microscopy – can overcome many of these limitations and open new vistas for researchers and clinicians to understand, diagnose and treat human diseases.

Holotomographic Microscopy – New era of microscopy Tomocube’s holotomography series utilize optical diffraction tomography (ODT), which enables users to quantitatively and noninvasively investigate biological cells and tissues. ODT reconstructs the 3D refractive index (RI) distributions of live cells and by doing so, provides structural and biochemical information about the cell including dry mass, morphology, and dynamics of the cellular membrane.

Tomocube_Label-free 3D Live Cell Imaging_Holotomography_HT-1H

5 Key features


Zero stress

Label-free imaging

Intact live cell imaging

Long-term imaging with short time interval

Time saving

No sample preparation and Rapid 3D cell imaging

High quality 3D

Optical resolution below 200 nm (Max. 110 nm)

Quantitative bioimaging

RI distribution, local cytoplasmic concentration, dry mass, calculated morphological parameters

Tomocube_Label-free 3D Live Cell Imaging_Holotomography_TomoDish

Technical specification

Tomocube_Label-free 3D Live Cell Imaging_Holotomography_HT1H


Holotomographic Microscopy
Tomocube_Label-free 3D Live Cell Imaging_Holotomography_HT-2H System


Holotomographic microscopy
with 3D fluorescence imaging capability

Environmental requirement


Innovate the way we see life